The Citizens have made a poor start to defending their title with defeats to Tottenham Hotspur but have since won 3 times in a row against Norwich City, Arsenal, and Leicester City.
Manchester City thrashed Norwich and Arsenal 5-0 at the Etihad at the start of the season, as they beat a quintet of unanswered goals against Everton at home on the final day of the 2020-21 season.
If Man City can win another 5-goal tie against the Saints this weekend, they will be the first team in English Premier League history to register a successive home win for such goals.
Since then Everton in 1931 his team has been able to accomplish this amazing feat, while Aston Villa were the first to put their name in the history books with that record in 1899.
The city lies fifth in the Premier League table ahead of their visit to Southampton, who have lost eight of their nine away games against top-flight champions since 2012.